Abstract:

Hemophilia is a genetic disease in which the affected person has a coagulation disorder to prevent bleeding. The most common treatment for this disease is the use of coagulation factors, and due to the high price of these drugs, hemophilia has become one of the most expensive diseases worldwide. Many studies around the world have shown that overweight and obesity can increase drug use, increase bleeding, and joint damage in hemophilia patients. The present study is the first study conducted in Iran that has addressed the issue of overweight and obesity in hemophilia. The results of this study showed that for every unit increase in body mass index (BMI), weekly drug use in hemophilia patients increases by more than 500 units (IU). Also, a significant direct relationship was observed between BMI and the number of bleeding and joint damage. Fitness management and implementation of weight loss programs in hemophilia patients not only improves the health status of patients and enhances their quality of life, but can also create economic savings of more than 2,300 billion Tomans annually in the country’s health budget by reducing drug consumption.